Complex 2esj

Legend

Pocket colors by molecule type

RNA

Protein

DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique	X-ray
Experimental resolution	2.20
System mass	15.62 kDa
Deposition year	2005
Molecule type	RNA
# RNA entities	1
Organism	N/A
RCSB PDB Entry	2esj
Reference	Francois B.. 2005. Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding Nucleic Acids Research
Equivalence Class	NR_all_71199.7 BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

Favourable

Intermediate

Unfavourable

Not available

Score	Threshold	Meaning
SiteScore	< 0.8	Non-drug binding site
SiteScore	0.8 – 1.0	Potential drug binding site
SiteScore	> 1.0	Promising binding site
D Score	< 0.83	Undruggable
D Score	0.83 – 0.98	Difficult
D Score	> 0.98	Druggable

Tick a pocket below to highlight it in the 3D structure above.

Pocket 1

Compound	LIV
Residue	. / 50
Chain	C / A
Non-redundant	True
Interacting RNA chains	B/B, A/A
RNA environment detailled	RNA-only
RNA environment global	RNA
RNA family chains	A/A: rRNA, B/B: rRNA
RNA family global	rRNA
Volume	78.20 Å³
Hydrophobicity	0.216
Hydrophilicity	0.915
Buriedness	0.599
Don/acc character	3.554
SiteScore	0.763
D Score	0.558
Kd	—

Pocket 2

Compound	LIV
Residue	. / 51
Chain	D / B
Non-redundant	True
Interacting RNA chains	B/B, A/A
RNA environment detailled	RNA-only
RNA environment global	RNA
RNA family chains	A/A: rRNA, B/B: rRNA
RNA family global	rRNA
Volume	110.10 Å³
Hydrophobicity	0.151
Hydrophilicity	0.884
Buriedness	0.577
Don/acc character	1.828
SiteScore	0.939
D Score	0.792
Kd	—