Complex 2bte
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.90 |
| System mass | 260.23 kDa |
| Deposition year | 2005 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 2bte |
| Reference | Tukalo Michael, Yaremchuk Anna, Fukunaga Ryuya, Yokoyama Shigeyuki, Cusack Stephen. 2005. The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer–editing conformation Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_23989.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 2AD |
| Residue | . / 1893 |
| Chain | U / A |
| Non-redundant | True |
| Interacting RNA chains | B/B |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | B/B: tRNA |
| RNA family global | tRNA |
| Volume | 408.86 Å3 |
| Hydrophobicity | 0.663 |
| Hydrophilicity | 1.086 |
| Buriedness | 0.794 |
| Don/acc character | 0.851 |
| SiteScore | 1.064 |
| D Score | 1.062 |
| Kd | — |
| Compound | 2AD |
| Residue | . / 1895 |
| Chain | OA / D |
| Non-redundant | True |
| Interacting RNA chains | D/E |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | D/E: tRNA |
| RNA family global | tRNA |
| Volume | 389.31 Å3 |
| Hydrophobicity | 0.684 |
| Hydrophilicity | 0.998 |
| Buriedness | 0.796 |
| Don/acc character | 0.814 |
| SiteScore | 1.074 |
| D Score | 1.092 |
| Kd | — |