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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 1z58

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.80
System mass 934.32 kDa
Deposition year 2005
Molecule type RNA
# RNA entities 1
Organism Deinococcus
RCSB PDB Entry 1z58
Reference Amit Maya, Berisio Rita, Baram David, Harms Joerg, Bashan Anat, Yonath Ada. 2005. A crevice adjoining the ribosome tunnel: Hints for cotranslational folding FEBS Letters
Equivalence Class NR_all_88987.11
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound RAP
Residue . / 2881
Chain B / 2
Non-redundant True
Interacting RNA chains A/2
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains A/2: rRNA
RNA family global rRNA
Volume 417.09 Å3
Hydrophobicity 0.142
Hydrophilicity 1.311
Buriedness 0.779
Don/acc character 2.003
SiteScore 1.082
D Score 0.980
Kd