Complex 1tfw

Legend

Pocket colors by molecule type

RNA

Protein

DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique	X-ray
Experimental resolution	2.20
System mass	231.12 kDa
Deposition year	2004
Molecule type	RNA/Protein
# RNA entities	1
Organism	N/A
RCSB PDB Entry	1tfw
Reference	Xiong Yong, Steitz Thomas A.. 2004. Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template Nature
Equivalence Class	NR_all_65598.3 BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

Favourable

Intermediate

Unfavourable

Not available

Score	Threshold	Meaning
SiteScore	< 0.8	Non-drug binding site
SiteScore	0.8 – 1.0	Potential drug binding site
SiteScore	> 1.0	Promising binding site
D Score	< 0.83	Undruggable
D Score	0.83 – 0.98	Difficult
D Score	> 0.98	Druggable

Tick a pocket below to highlight it in the 3D structure above.

Pocket 1

Compound	ATP
Residue	. / 1501
Chain	L / B
Non-redundant	True
Interacting RNA chains	B/H
RNA environment detailled	protein, ion
RNA environment global	RNA/Protein
RNA family chains	B/H: tRNA
RNA family global	tRNA
Volume	548.80 Å³
Hydrophobicity	0.120
Hydrophilicity	1.602
Buriedness	0.841
Don/acc character	0.840
SiteScore	1.096
D Score	0.922
Kd	—

Pocket 2

Compound	ATP
Residue	. / 1502
Chain	N / D
Non-redundant	True
Interacting RNA chains	D/I
RNA environment detailled	protein, ion
RNA environment global	RNA/Protein
RNA family chains	D/I: tRNA
RNA family global	tRNA
Volume	645.18 Å³
Hydrophobicity	0.152
Hydrophilicity	1.479
Buriedness	0.846
Don/acc character	0.812
SiteScore	1.099
D Score	0.966
Kd	—