Complex 1lc4

Legend

Pocket colors by molecule type

RNA

Protein

DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique	X-ray
Experimental resolution	2.54
System mass	15.65 kDa
Deposition year	2002
Molecule type	RNA
# RNA entities	1
Organism	N/A
RCSB PDB Entry	1lc4
Reference	Vicens Quentin, Westhof Eric. 2002. Crystal Structure of a Complex between the Aminoglycoside Tobramycin and an Oligonucleotide Containing the Ribosomal Decoding A Site Chemistry & Biology
Equivalence Class	NR_all_71199.7 BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

Favourable

Intermediate

Unfavourable

Not available

Score	Threshold	Meaning
SiteScore	< 0.8	Non-drug binding site
SiteScore	0.8 – 1.0	Potential drug binding site
SiteScore	> 1.0	Promising binding site
D Score	< 0.83	Undruggable
D Score	0.83 – 0.98	Difficult
D Score	> 0.98	Druggable

Tick a pocket below to highlight it in the 3D structure above.

Pocket 1

Compound	TOY
Residue	. / 47
Chain	C / A
Non-redundant	True
Interacting RNA chains	A/A, B/B
RNA environment detailled	RNA-only
RNA environment global	RNA
RNA family chains	A/A: rRNA, B/B: rRNA
RNA family global	rRNA
Volume	108.73 Å³
Hydrophobicity	0.146
Hydrophilicity	0.857
Buriedness	0.567
Don/acc character	3.066
SiteScore	0.786
D Score	0.601
Kd	—

Pocket 2

Compound	TOY
Residue	. / 48
Chain	D / B
Non-redundant	True
Interacting RNA chains	A/A, B/B
RNA environment detailled	RNA-only
RNA environment global	RNA
RNA family chains	A/A: rRNA, B/B: rRNA
RNA family global	rRNA
Volume	93.64 Å³
Hydrophobicity	0.085
Hydrophilicity	0.887
Buriedness	0.553
Don/acc character	4.570
SiteScore	0.764
D Score	0.575
Kd	—