Complex 1kc8

Legend

Pocket colors by molecule type

RNA

Protein

DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique	X-ray
Experimental resolution	3.01
System mass	1459.04 kDa
Deposition year	2001
Molecule type	RNA/Protein
# RNA entities	1
Organism	Haloarcula
RCSB PDB Entry	1kc8
Reference	Hansen Jeffrey L., Moore Peter B., Steitz Thomas A.. 2003. Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit Journal of Molecular Biology
Equivalence Class	NR_all_26150.5 BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

Favourable

Intermediate

Unfavourable

Not available

Score	Threshold	Meaning
SiteScore	< 0.8	Non-drug binding site
SiteScore	0.8 – 1.0	Potential drug binding site
SiteScore	> 1.0	Promising binding site
D Score	< 0.83	Undruggable
D Score	0.83 – 0.98	Difficult
D Score	> 0.98	Druggable

Tick a pocket below to highlight it in the 3D structure above.

Pocket 1

Compound	BLS
Residue	. / 9001
Chain	EA / A
Non-redundant	True
Interacting RNA chains	A/A
RNA environment detailled	ion, other
RNA environment global	RNA/Other
RNA family chains	A/A: rRNA
RNA family global	rRNA
Volume	796.79 Å³
Hydrophobicity	0.237
Hydrophilicity	1.051
Buriedness	0.682
Don/acc character	1.679
SiteScore	1.139
D Score	1.006
Kd	—

Pocket 2

Compound	BLS
Residue	. / 9002
Chain	FA / A
Non-redundant	False
Interacting RNA chains	A/A
RNA environment detailled	other
RNA environment global	RNA/Other
RNA family chains	A/A: rRNA
RNA family global	rRNA
Volume	354.66 Å³
Hydrophobicity	0.415
Hydrophilicity	1.029
Buriedness	0.697
Don/acc character	1.182
SiteScore	0.986
D Score	0.811
Kd	—