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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 1i9v

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 2.60
System mass 25.45 kDa
Deposition year 2001
Molecule type RNA
# RNA entities 1
Organism Saccharomyces
RCSB PDB Entry 1i9v
Reference Mikkelsen Nils E., Johansson Kenth, Virtanen Anders, Kirsebom Leif A.. 2001. [] Nature Structural Biology
Equivalence Class NR_all_83593.11
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound NMY
Residue . / 200
Chain B / A
Non-redundant True
Interacting RNA chains A/A
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains A/A: tRNA
RNA family global tRNA
Volume 111.48 Å3
Hydrophobicity 0.009
Hydrophilicity 1.428
Buriedness 0.704
Don/acc character 0.352
SiteScore 0.836
D Score 0.489
Kd