Complex 1i2y
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 1.66 |
| System mass | 21.03 kDa |
| Deposition year | 2001 |
| Molecule type | RNA/DNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 1i2y |
| Reference | TERESHKO VALENTINA, WALLACE SCOT T., USMAN NASSIM, WINCOTT FRANCINE E., EGLI MARTIN. 2001. X-ray crystallographic observation of “in-line” and “adjacent” conformations in a bulged self-cleaving RNA/DNA hybrid RNA |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SPM |
| Residue | . / 300 |
| Chain | G / D |
| Non-redundant | False |
| Interacting RNA chains | D/D, C/C |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | C/C: RNA/DNA_hybrid, D/D: RNA/DNA_hybrid |
| RNA family global | RNA/DNA_hybrid |
| Volume | 106.33 Å3 |
| Hydrophobicity | 0.064 |
| Hydrophilicity | 0.670 |
| Buriedness | 0.453 |
| Don/acc character | 3.962 |
| SiteScore | 1.057 |
| D Score | 0.993 |
| Kd | — |