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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 11ss

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.03
System mass 458.38 kDa
Deposition year 2026
Molecule type RNA/DNA/Protein
# RNA entities 1
Organism N/A
RCSB PDB Entry 11ss
Reference Malik Radhika, Johnson Robert E., Prakash Louise, Prakash Satya, Aggarwal Aneel K.. 2026. Molecular basis of DNA polymerase ζ’s reverse transcriptase activity Nature Communications
Equivalence Class NR_all_94138.1
BGSU version: 4.61

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound DCP
Residue . / 1602
Chain J / A
Non-redundant True
Interacting RNA chains H/X
RNA environment detailled DNA, protein, ion
RNA environment global RNA/DNA/Protein
RNA family chains H/X: synthetic construct
RNA family global synthetic construct
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd —