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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 11el

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 RNA

 Protein

 DNA

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System information

Experimental technique Electron Microscopy
Experimental resolution 3.20
System mass 2151.70 kDa
Deposition year 2026
Molecule type RNA/Protein
# RNA entities 1
Organism Escherichia
RCSB PDB Entry 11el
Reference Raskar Tushar, Costello Alan, Badran Ahmed H., Fraser James S.. 2026. Structural adaptations for enhanced translation kinetics in evolved ribosomes preprint (openRxiv)
Equivalence Class NR_all_83717.187
BGSU version: 4.52

Pockets List

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Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound SPM
Residue . / 6221
Chain FN / a
Non-redundant True
Interacting RNA chains BA/a
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains BA/a: rRNA
RNA family global rRNA
Volume 142.35 Å3
Hydrophobicity 0.061
Hydrophilicity 1.157
Buriedness 0.677
Don/acc character 3.177
SiteScore 0.783
D Score 0.517
Kd