Complex 10qm
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.49 |
| System mass | 1360.99 kDa |
| Deposition year | 2026 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 10qm |
| Reference | Lee Isabel J., Li Qi, Raskar Tushar, Pellegrino Jenna, Ecker Andrew K., Howard Sara Y., Fraser James S., Seiple Ian B.. 2026. Structure-based design and synthesis of group A streptogramins that bind to the nascent peptide exit tunnel of the ribosome European Journal of Medicinal Chemistry |
| Equivalence Class |
NR_all_83717.187
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | A1C7K |
| Residue | . / 3184 |
| Chain | GH / I |
| Non-redundant | True |
| Interacting RNA chains | A/I |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/I: rRNA |
| RNA family global | rRNA |
| Volume | 419.15 Å3 |
| Hydrophobicity | 0.695 |
| Hydrophilicity | 0.968 |
| Buriedness | 0.760 |
| Don/acc character | 1.615 |
| SiteScore | 1.116 |
| D Score | 0.976 |
| Kd | — |